Five could definitely kill both Frenchie and MM very easily, provided he realized in time that he'd need to hold his breath against anything Frenchie threw out of his pockets.

"He has many of those small electrolyte packs, aussi," Frenchie informed him. "Me, I try not to let the hangover happen at all."

Just keep on drinking until you ran out of booze, and then it was time to get high. A sound strategy that definitely always worked.